Correlation betweenumuCinduction andSalmonellamutagenicity assay for quinolone antimicrobial agents
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چکیده
منابع مشابه
Pharmacodynamics of Quinolone Antimicrobial Agents
Pharmacodynamics describes the relationship between measures of drug levels in serum and tissue fluids and the antimicrobial and toxicologic effects of drugs (5, 10, 17, 49). While there have been numerous studies describing the pharmacokinetics of fluoroquinolones in serum and tissues, there has been much less emphasis on describing the time course of antimicrobial activity with these drugs. T...
متن کاملQuinolone Antimicrobial Agents, 3rd Edition
The quinolone class is one of the more important classes of antimicrobial agents discovered in recent years and one of the most widely used classes of antimicrobial drugs in clinical medicine. Their broad spectrum of activity and pharmacokinetic properties make the quinolone agents ideal for treating a variety of infections. Their clinical importance is further demonstrated by their activity ag...
متن کاملIn vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei.
Imipenem was highly active and bactericidal against all 100 strains of Pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. The addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. Ciprofloxacin and norfloxacin showed poor activity against test strains.
متن کاملSusceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to antimicrobial agents and characterization of quinolone-resistant strains.
OBJECTIVES To study the susceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to several antimicrobial agents and to investigate the mechanisms of nalidixic acid and ciprofloxacin resistance. METHODS The disc diffusion method was employed to study the susceptibility of 49 C. hyointestinalis subsp. hyointestinalis strains of reindeer and bovine origin to 12 different antimicro...
متن کاملThe newest quinolone antibacterial agents and theophylline.
486 Communications to the Editor well described by Pepe and Marini#{176}and is an important cause of hypotension in mechanically ventilated patients. The lungs are unable to exhale to FRC at the start of the next mechanically initiated inspiration because of airway obstruction. Positive end expiratorv intrathoracic pressure builds up, although this cannot be shown on the ventilator manometer. T...
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ژورنال
عنوان ژورنال: FEMS Microbiology Letters
سال: 1993
ISSN: 0378-1097,1574-6968
DOI: 10.1111/j.1574-6968.1993.tb06458.x